甲状腺功能亢进患者碘营养状态和维生素D水平评估

Evaluation of iodine nutrition status and vitamin D level in hyperthyroidism patients

目的 在甲状腺功能亢进症（以下简称甲亢）患者中评估碘营养状态及维生素D水平,探讨其对甲亢疾病的影响.方法 甲亢住院患者116例,测定甲状腺功能、尿碘、血清25羟维生素D [25 （OH） D]水平.以尿碘和25 （OH）D的中位数和构成比评估甲亢患者碘及维生素D的营养状态.结果 甲亢患者中尿碘中位数224.9μg/L,碘超标准摄入组占甲亢患者的59.48％（碘过量组12.93％、超足量组46.55％）.25 （OH）D中位数7.19 ng/ml,维生素D缺乏占92.24％.结论 甲亢患者中需要关注碘营养状态;补充维生素D,对治疗甲亢、维护甲亢患者的骨骼、肌肉健康非常重要.

Objective To evaluate iodine nutrition status and vitamin D level in hyperthyroidism patients and explore their impacts on the pathogenesis of hyperthyroidism.Methods Totally 116 inpatients of hyperthyroidism were tested for serum thyroid function,urine iodine and serum 25-OH-D.Median and component ratio of urine iodine and 25-OH-D were used to evaluate nutrition status.Results The median of urine iodine was 224.9 μg/L,while the component ratio of iodine excessive-intake was 59.48% （12.93% in excessive group and 46.55% in sufficient group）.The median of vitamin D was 7.19 ng/ml while as deficiency group accounted for 93.2% in hyperthyroidism patients.Conclusions Attention should be paid to excessive intake iodine in hyperthyroidism patients.Vitamin D supplementation is important for treating hyperthyroidism and maintaining the health of skeleton and muscle.