2例垂体萎缩患者性功能障碍治疗始末

Literature review of two cases of pituitary gland atrophy leading to erectile dysfunction

目的:补充引起勃起功能障碍的病因之一:垂体萎缩,分析性腺功能不足导致激素水平低下与勃起功能障碍、性欲障碍的关系。方法:回顾2例因垂体萎缩导致勃起功能障碍患者的详细病史、体格检查、实验室检查、诊断分析和治疗经过。结果:病例一在给予雄激素补充治疗后,勃起功能和性欲反应良好;病例二给予抗焦虑药、PDE5抑制剂和雄激素补充治疗后,除了患者自觉晨勃硬度较前改善外,性欲和同房成功率均无改善。结论:雄激素对性欲的产生和性功能的维持十分重要,但又不是唯一的因素,还受心理因素的影响。

Objectives： To probe into the relationship between hypogonadotropic hypogonadism and erectile dysfunction（ ED） or libido disorder since the pituitary gland atrophy is one of pathogenesis in erectile dysfunction.Methods： The clinical histories,physical examinations,laboratory tests,diagnostic analysis and treatment experiences in the two pituitary gland atrophy cases which leading to ED were retrospectively summarized. Results： One case who accepted testosterone replacement therapy had a good therapeutic effect and sexual response in treating erectile function. However,the other case who accepted antianxiety drugs,type-5 phosphodiesterase inhibitors and testosterone replacement therapy had no improvement in libido and intercourse rate except hardness in early morning suddenly. Conclusion： Androgen is very important in maintaining libido and sexual response,which are also affected by psychological factors.