大叶桉煎剂对烧伤残余创面的效果观察及其部分机理探析

Observation on Effects of Folium Eucalypti Robustae Decoction on Residual Burn Wound and Analysis of its Mechanism

目的:探讨大叶桉煎剂治疗烧伤残余创面的临床疗效及部分作用机制。方法:选取2015年1月至2016年6月陕西省商洛市中医医院外科收治的烧伤患者74例,随机分成对照组和观察组,每组37例。观察组和对照组分别予大叶桉煎剂及消毒剂涂抹创面,1次/d。观察2组患者创面外观恢复情况,并判定临床疗效及对细菌的清除率。结果:1)观察组残余创面外观改善显著优于对照组,差异有统计学意义(P<0.05);2)对照组残余创面愈合时间为(15.7±1.9)d,而观察组愈合时间为(24.1±2.2)d,明显短于对照组,且观察组7 d及14 d愈合百分率均高于对照组差异有统计学意义(P<0.05);3)观察组有效率94.59%,对照组有效率78.38%,2组患者临床总有效率比较差异有统计学意义(P<0.05);4)对照组在7 d及14 d对金黄色葡萄球菌、耐甲氧金黄色葡萄球菌及铜绿假单胞杆菌的清除率均明显较快,差异有统计学意义(P<0.05)。结论:大叶桉煎剂治疗烧伤残余创面有明显治疗效果,且价格合理,值得推广。

Objective： To analyze curative effect of Folium Eucalypti Robustae decoction in the treatment of residual burn wound and its mechanism. Methods： A total of 74 patients who were admitted to burn department from January 2015 to June 2016 were randomly divided into control group and observation group,with 37 cases in each group. Observation group and control group were respectively treated with Folium Eucalypti Robustae decoction and skin antiseptic,1 time a day. The residual burn wound of two groups were observed,and the clinical effect and bacterium removing were determined. Results： 1） The residual burn wound of observation group was significantly better than the control group（ P〈0. 05）. 2） The healing time of residual burn wound in observation group was（ 15. 7 ± 1. 9） days,and was（ 24. 1 ± 2. 2） days for control group. Meanwhile the healing rate of residual burn wound in observation group of 7 and 14 days was higher than that of control group. 3） There was a remarkable difference（ P〈0. 05） in the effective rate between the observation group（ 94. 59%） and the control group（ 78. 38%）. 4） The removing rate of staphylococcus aureus,methicillin resistant staphylococcus aureus and pseudomonas aeruginosa of observation group in the 7 and 14 days were all significantly faster than that of control group（ P〈0. 05）. Conclusion： Folium Eucalypti Robustae decoction can treat residual burn wound effectively with low price. Consequently,it is worthy of promotion.