植物细胞选择性自噬研究进展

Review of Selective Autophagy in Plant Cell

植物在生长发育和响应环境胁迫过程中不断产生受损的细胞器和蛋白质等,这些物质必须被及时且适宜的降解。其中,细胞自噬就是一个在进化上保守的主要降解途径。自噬体通过受体蛋白选择性地识别并靶向特异的组分和蛋白复合物,然后传递至液泡中降解,使其能够循环再利用,从而调节细胞内的关键反应过程。近些年的研究揭示了自噬在植物生命活动的多个过程中均发挥重要作用。本文中主要综述了植物细胞选择性自噬的最新研究进展,包括自噬体形成过程、货物识别、分类以及在生长发育、植物免疫和响应非生物胁迫中的作用。

Plants continuously produce damaged organelles and proteins in the process of growth and response to environmental stresses,which must be timely and appropriately degraded.Autophagy is a major cellular degradation pathway conserved during evolution in plants.Autophagosomes selectively recognize and target specific compartments and protein complexes through cargo receptor proteins,then deliver them to the vacuole for degradation and recycling,which regulates the critical reactions within the cell.Researches in recent years have revealed the importance of autophagy in many aspects of plant life.In this article,the latest advances of plant cell selective autophagy are reviewed,including autophagosome formation,cargo recognition and types of selective autophagy,and the role in growth and development,immune,and response to abiotic stress.