互联网随访对慢性乙型肝炎出院患者抗病毒治疗遵医行为及生活质量的影响

Effect of Internet-based follow-up on antiviral treatment compliance and quality of life in discharged patients with chronic hepatitis B

目的观察互联网随访模式对慢性乙型肝炎(chronic hepatitis B,CHB)出院患者抗病毒治疗遵医行为及生活质量的影响.方法选择2016-02/2017-05在杭州市余杭区第二人民医院行抗病毒治疗的85例CHB出院患者,按随机数字表法分为观察组(44例)及对照组(41例).对照组患者采用常规的电话随访方式,观察组采用互联网随访模式,以互联网服务平台(手机微信、QQ、电子邮件)为载体,发布CHB健康教育知识,指导服药及定期复诊等,均随访6 mo.分别于随访前随访前1 d、随访1、3、6 mo分别发放量表,统计两组患者各时间点遵医行为及生活质量情况.结果最终有75例患者完成了本研究(对照组37例,观察组38例).两组患者在随访前1 d及随访1 mo时遵医依从程度及生活质量差异均无显著统计学意义(P>0.05).随着随访时间的延长,随访1 mo后开始两组患者遵医依从程度及生活质量评分均呈上升趋势.至随访6 mo时,观察组遵医依从程度及生活质量评分显著高于随访前1 d,亦显著高于随访6 mo时的对照组.结论互联网随访模式较常规的电话随访应用效果更好,对CHB出院患者遵医行为及生活质量均有明显改善作用,值得临床推广应用.

AIM To investigate the effect of Internet-based follow-up on antiviral treatment compliance and quality of life in discharged patients with chronic hepatitis B（CHB）.METHODS Eighty-five discharged CHB patients who received antiviral therapy at Yuhang District Second People’s Hospital of Hangzhou City from February 2016 to May 2017 were randomly divided into either an experimental group（n = 44） or a control group（n = 41）.The patients in the control group were given routine telephone follow-up for 6 mo, and the patients in the experimental group were given Internet-based follow-up by using Internet service platforms（WeChat, QQ, or E-mail）for 6 mo. The antiviral treatment compliance and quality of life were evaluated using questionnaires at 1 d before follow-up and 1, 3,and 6 mo after follow-up. The compliance and quality of life were then compared between the two groups at four time points.RESULTS Seventy-five patients completed the study（38 cases in the experimental group and 37 cases in the control group）. The compliance and life quality did not differ significantly between the two groups at 1 d before follow-up and1 mo after follow-up in the two groups.With the extension of follow-up, the degree of compliance and the score of quality life showed an ascending trend from 1 mo after follow-up. At 6 mo after follow-up, the degreeof compliance and the score of life quality in the experimental group were significantly high than those at 1 d before follow-up, and those in the control group at the same time point.CONCLUSION Internet-based follow-up performs better than traditional telephone follow-up with regard to improving the antiviral treatment compliance and quality of life in discharged CHB patients.