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全直肠系膜切除术与传统手术治疗直肠癌的疗效比较 被引量:2

Comparison of the efficacy of total mesorectal excision and traditional surgery in the treatment of rectal cancer
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摘要 目的研究腹腔镜全直肠系膜切除术与传统手术治疗直肠癌的效果。方法选取160例直肠癌患者,按照随机数字表法分为观察组和对照组,每组80例,对照组采用传统的直肠癌根治术,观察组采用腹腔镜全直肠系膜切除术。观察两组患者的治疗效果,包括手术时间、肠道功能恢复时间、术后下床时间、住院时间、出血量及不良反应情况,包括局部复发率、泌尿功能障碍、性功能减退、博起障碍、射精障碍、阴道疼痛等,以及1年期生存率、2年期生存率、保肛率等情况。结果观察组患者手术时间明显比对照组长,肠道功能恢复时间、术后下床时间、住院时间、出血量明显优于对照组,差异均有统计学意义(P<0.05);观察组患者的局部复发率、泌尿功能障碍、性功能减退、勃起障碍、射精障碍、阴道疼痛情况均优于对照组,差异有统计学意义(P<0.05);观察组2年期生存率明显高于对照组,差异有统计学意义(P<0.05)。结论直肠癌应用全直肠系膜切除术治疗,与传统的直肠癌根治术相比,能够明显提高治疗效果,减少并发症,延长患者生存期,值得在临床上推广应用。 Objective To study the effect of laparoseopic total mesoreetal excision and traditional surgery in the treat- ment of rectal cancer. Methods A total of 160 patients with rectal cancer were randomly selected, and were divided in- to observation group and control group according to random number table method, with 80 patients in each group. The control group was given traditional radical resection of rectal cancer, and the observation group was given laparoscopic total mesoreetal excision.The therapeutic effect of the two groups of patients was observed, including the time of opera- tion, the recovery time of intestinal function, the off-bed time, length of stay, the amount of bleeding, and adverse reac- tions, including local recurrence rate, urinary dysfunction, sexual dysfunction, erectile disorders, ejaculatory disorders, vaginal pain, etc., as well as one-year survival rate, two-year survival rate, and anal preservation rate. Results The operation time in the observation group was significantly longer than that in the control group. The intestinal function recovery time, postoperative off-bed time, length of stay, the amount of bleeding were significantly better than those in the control group, and the differences were statistically significant(P〈0.05); the local recurrence rate, urinary dysfunc- tion, sexual dysfunction, erectile dysfunction, ejaculation and vaginal pain were significantly better in the observation group than in the control group, and the differenceswere statistically significant(P〈0.05); the two-year survival rate in the observation group was significantly higher than that in the control group, and the difference was statistically signifi- cant(P〈0.05). Conclusion Total mesorectal excision in the treatment of rectal cancer, compared with traditional radical resection of rectal cancer, can significantly improve the curative effect, reduce the complications and prolong the survival of patients, which is worthy of clinical promotion and application.
作者 刘红光 LIU Hongguang(Proctology Department,Zouping County People's Hospital in Shandong Province,Zouping 256200,Chin)
出处 《中国现代医生》 2017年第32期36-39,共4页 China Modern Doctor
关键词 全直肠系膜切除术 直肠癌根治术 保肛率 生存率 Total mesoreetal excision Radical resection of rectal cancer Anal preservation rate Survival rate
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