肥胖与非肥胖OSAHS患者的临床特点与危险因素分析

Clinical Characteristics and Risk Factors of Obese and Non Obese Patients With OSAHS

目的探究肥胖与非肥胖阻塞性睡眠呼吸暂停综合征患者临床特点与危险因素。方法选取2015年3月—2017年3月我院收治的经多导睡眠监测(PSG)确诊的阻塞性睡眠呼吸暂停综合征(OSAS)的患者200例作为研究对象,另选取同期于我院进行PSG的非OSAS患者50例作为对照组。将OSAS患者分为肥胖组和非肥胖组。对OSAS患者与非OSAS志愿者的基线数据进行比较;对肥胖组和非肥胖组患者的年龄、颈围、臂围、腰围、腰臀比、腰围身高比及睡眠呼吸暂停低通气指数(AHI)进行比较;对各影响因素进行相关性分析。结果OSAS患者的颈围、臂围、腰围、腰臀比、腰围身高比及AHI高于非OSAS组;与非肥胖组相比,肥胖组患者以上指标升高;年龄降低;腰围、腰臀比及腰围身高比为肥胖OSAS患者的主要相关因素;年龄、颈围是非肥胖OSAS患者患病的主要相关因素。结论腰围、腰臀比及腰围身高比是肥胖患者发生OSAS的主要危险因素,而年龄及颈围是非肥胖患者发生OSAS的主要危险因素。

Objective To explore the clinical characteristics and risk factors of obese and non obese patients with obstructive sleep apnea syndrome. Methods Polysomnography from March 2015 to March 2017 by our hospital （PSG） diagnosed as obstructive sleep apnea syndrome （OSAS） patients with 200 cases as the research object were selected by PSG in our hospital 50 cases of non OSAS patients as the control group. The OSAS patients were divided into obesity group and non obesity group. Baseline data were compared between OSAS patients and non OSAS volunteers. The age, neck circumference, arm circumference, waist circumference, waist hip ratio, waist height ratio and sleep apnea hypopnea index （AHI） were compared between obese and non obese patients; The correlation analysis of each influencing factor Was carried out. Results The neck circumference, arm circumference, waist circumference, waist hip ratio, waist circumference, height ratio and AHI of OSAS patients were significantly higher than those of non OSAS group. Compared with non obese group, the above indexes were significantly increased in obese group. Age decreased significantly. Waist circumference, waist to hip ratio and waist to height ratio are the main factors associated with obesity in OSAS patients. Age and neck circumference were the main factors associated with the prevalence of non obese OSAS patients. Conclusion Waist circumference, waist hip ratio and waist to height ratio are the main risk factors for OSAS in obese patients, while age and neck circumference are the major risk factors for OSAS in non obese patients.