舒芬太尼、芬太尼复合咪唑安定辅助椎管内麻醉效果比较

Comparison of the Effect of Sufentanil, Fentanyl and Midazolam in Spinal Anesthesia

目的比较分析在患者手术过程中应用舒芬太尼与芬太尼复合咪唑安定辅助椎管内麻醉的临床效果。方法将2016年3月—2017年3月我院收治的90例手术患者纳入本次研究,将手术患者依照麻醉药物的不同分成芬太尼组(n=45)和舒芬太尼组(n=45),对两组手术患者分别实施芬太尼+咪唑安定联合辅助椎管内麻醉与舒芬太尼+咪唑安定联合辅助椎管内麻醉。结果芬太尼组手术患者给药后及术中的心率、血压与舒芬太尼组相比,差异有统计学意义(P<0.05),且舒芬太尼组优于芬太尼组。结论相较于实施芬太尼+咪唑安定,在患者手术中应用舒芬太尼+咪唑安定的麻醉效果更为显著。

Objective To comparative analyze the clinical effect of sufentanil and fentanyl combined with midazolam in spinal anesthesia during the operation of patients. Methods From March 2016 to March 2017, 90 cases of surgical patients in our hospital were included in this study, they were divided into fentanyl group（n=45） and sufentanil group（n=45） according to the different anesthetic drugs, two groups of patients were given fentanyl ＋ midazolam combined with spinal anesthesia and sufentanil ＋ midazolam combined with spinal anesthesia respectively. Results The postoperative heart rate and blood pressure in the fentanyl group were significantly different from those in the sufentanil group（P〈0.05）, the sufentanil group was better than the fentanyl group. Conclusion Compared with fentanyl ＋ midazolam, the effect of sufentanil combined with midazolam is more significant in patients undergoing surgery.