高同型半胱氨酸(Hhcy)血症脑梗死患者的临床特点分析

Clinical Characteristics of Cerebral Infarction Patients With High Homocysteine(Hhcy)

目的分析研究高同型半胱氨酸血症脑梗死患者的临床特点。方法利用血浆同型半胱氨酸的浓度不同将患者分为两组,观察组40例,均为高同型半胱氨酸血症脑梗死患者,且Hcy血浆的浓度大于15μmol/L;对照组40例,为正常水平的同型半胱氨酸脑梗死患者,且血浆的浓度处于5～15μmol/L。结果观察组与对照组的神经功能缺损程度对比,差异无统计学意义(P>0.05);观察组出现复发脑梗死或病情进展的概率高于对照组(P<0.05)。结论高同型半胱氨酸(Hhcy)血症脑梗死患者易复发脑梗死,且病情容易进展,风险性较高,需要引起临床的高度关注。

Objective To analyze the clinical characteristics of patients with hyperhomocysteinemia and cerebral infarction. Methods According to the concentration of plasma homocysteine, patients were divided into two groups, the observation group was consisted of 40 patients with hyperhomocysteinemia and cerebral infarction, and the plasma concentration of Hcy was higher than 15 μmol/L. In the control group, 40 patients were normal homocysteine cerebral infarction patients, and the plasma concentration was 5 to 15 μmol/L. Results There was no significant difference in the degree of neurologic impairment between the observation group and the control group（P〉0.05）. The probability of recurrence, cerebral infarction or disease progression in the observation group was higher than that in the control group（P〈0.05）. Conclusion High homocysteine（Hhcy） patients with cerebral infarction are prone to recurrent cerebral infarction, and the disease is easy to progress, and has and high risk, needs clinical attention.