老年性心力衰竭患者血清cTnI与血浆BNP联合检测的临床意义

Clinical significance of combined detection of serum cTnI and plasma BNP in elderly patients with heart failure

目的:探讨老年性心力衰竭患者血清cTnI与血浆BNP联合检测的临床意义。方法:收治老年心衰患者100例作为观察组,选择同期健康体检的老年人100例作为对照组,均检测BNP和cTnI。结果:观察组血清cTnI浓度和血浆BNP浓度明显高于对照组,差异有统计学意义(P<0.05);随心功能分级级别的增高而增高,心功能分级不同,血清cTnI浓度和血浆BNP浓度也有显著的差异,差异有统计学意义(P<0.05)。结论:BNP和cTnI的浓度在CHF患者中均升高,与心衰程度呈正相关。BNP和cTnI的联合检测是评价老年心衰的重要指标,对判断患者心功能的状况有较高的临床价值。

Objective：To explore the clinical significance of combined detection of serum cTnI and plasma BNP in elderly patients with heart failure.Methods：100 elderly patients with heart failure were selected as the observation group,and 100 healthy elderly people were selected as the control group,both BNP and cTnI were detected.Results：The serum cTnI concentration and plasma BNP concentration in the observation group were significantly higher than those in the control group,and the difference was statistically significant（P〈0.05）.Increased with heart function classification level,there were significant differences in serum cTnI concentration and plasma BNP concentration in patients with different cardiac function grades,and the difference was statistically significant（P〈0.05）.Conclusion：The concentrations of BNP and cTnI are increased in patients with CHF,and positively correlated with the degree of heart failure.The combined detection of BNP and cTnI is an important indicator for the evaluation of elderly heart failure,and has a high clinical value in judging the cardiac function of the patients.