IgG4阳性桥本甲状腺炎超声表现

Ultrasonographic features of IgG4 positive Hashimoto thyroiditis

目的探讨IgG4阳性桥本甲状腺炎的超声表现。方法回顾性分析72例经我院手术病理证实为桥本甲状腺炎患者的临床和超声资料。根据免疫组化染色结果分为IgG4阳性组19例、IgG4阴性组53例。比较2组甲状腺的回声类型、合并结节情况、血流分布及甲状腺功能状态。结果 2组间甲状腺内低回声比例、网格样线样高回声比例、合并甲状腺癌比例差异均有统计学意义(P均<0.05),2组间伴发结节数量、甲状腺血流分布、甲状腺功能状态差异均无统计学意义(P均>0.05)。结论超声可为临床诊断IgG4阳性桥本甲状腺炎提供有价值的影像学依据。

Objective To investigate ultrasonographic manifestations of IgG4 positive Hashimoto thyroiditis. Methods Ultrasonographic and clinical features of histopathologically proved Hashimoto thyroiditis in 72 patients were retrospectively analyzed. The patients were divided into IgG4 positive group （n=19） and IgG4 negative group （n=53） according to immunohistochemical staining results. Echotexture, nodules, blood flow distribution and function status of thyroid were compared between the two groups. Results There were statistically significant differences in thyroid hypoechogenicity, linear echogenic strands and combined carcinomas （all P〈0.05）, while no statistically significant differences in nodule number, blood flow distribution nor function status of thyroid between the two groups were found （all P〉0.05）. Conclusion Ultrasonography can provide valuable imaging evidences for clinical diagnosis of IgG4 positive Hashimoto thyroiditis.