一种含吡啶配体氮杂环卡宾钯络合物(NHC)PdCl_2(Py)的合成及其高效催化偶联反应

Synthesis of a Pd-Pyridine N-Heterocyclic Carbene Complex (NHC)-PdCl_2(Py) and Its Efficient Application in Coupling Reaction

通过两步反应合成了一种卡宾配合物(NHC)Pd Cl2(Py),该配合物在有氧条件下能够高效地催化Suzuki偶联反应、Heck偶联反应和Sonogashira偶联反应.对于Suzuki偶联和Sonogashira偶联,仅使用0.1 mol%催化量的催化剂就能取得较好的收率.而对于不活泼的Heck偶联,使用1 mol%催化量的催化剂也能得到较好的产率.

A Pd-pyridine N-heterocyclic carbene complex（NHC）Pd Cl2（Py） has been synthesized through two steps and successfully applied as an effective catalyst for the Suzuki coupling reaction,Heck coupling reaction and Sonogashira coupling reaction.The catalyst demonstrates excellent catalytic activity in Suzuki coupling reaction and Sonogashira coupling reaction with a catalyst loading of 0.1 mol% and 1 mol% in Heck coupling reaction.