期刊文献+

合并下肢动脉粥样硬化斑块的缺血性卒中的危险因素

Risk factors for ischemic stroke complicated with atherosclerotic plaques of lower extremities
原文传递
导出
摘要 目的探讨伴下肢动脉粥样硬化斑块(lower extremity atherosclerosis, LEA)的急性缺血性卒中患者的危险因素。方法回顾性连续纳入发病7 d内住院的急性缺血性卒中患者。采用彩色多普勒探测仪检测LEA,确定并分析人口统计学特征、血管危险因素和实验室指标。结果共纳入156例急性缺血性卒中患者,138例伴有LEA。单变量分析显示,LEA组年龄[(69.5±11.8)岁对(60.4±11.5)岁;t=3.063,P=0.003]和高血压患者的比例(81.1%对55.6%;χ2=2.467,P=0.014)显著高于非LEA组。多变量logistic回归分析显示,在校正性别、基线收缩压、糖尿病、缺血性心脏病等混杂因素后,年龄[优势比(odds ratio, OR) 1.059,95%可信区间(confidence interval, CI)1.016~1.105;P=0.007]和高血压(OR 3.128,95% CI 1.084~9.026,P=0.035)为伴LEA的急性缺血性卒中的独立危险因素。结论年龄和高血压与伴LEA的急性缺血性卒中有关。 ObjectiveTo investigate the risk factors for acute ischemic stroke in patients with lower extremity atherosclerosis (LEA).MethodsThe consecutive patients with acute ischemic stroke admitted to hospital within 7 d after onset were enrolled retrospectively. Color Doppler flow imaging was used to detect LEA. The demographic characteristics, vascular risk factors, and laboratory parameters were identified and analyzed.ResultsA total of 156 patients with acute ischemic stroke were enrolled, including 138 with LEA. Univariate analysis showed that age (69.5±11.8 years vs. 60.4±11.5 years; t=3.063, P=0.003) and the proportion of patients with hypertension (81.1% vs. 55.6%; χ2=2.467, P=0.014) in the LEA group were significantly higher than those in the non-LEA group. Multivariate logistic regression analysis showed that after adjustment for confounders such as gender, baseline systolic blood pressure, diabetes mellitus, and ischemic heart disease, age (odds ratio [OR] 1.059, 95% confidence interval [CI] 1.016-1.105; P=0.007), and hypertension (OR 3.128, 95% CI 1.084-9.026, P=0.035) were the independent risk factors for acute ischemic stroke complicated with LEA.ConclusionsAge and hypertension are associated with acute ischemic stroke complicated with LEA.
出处 《国际脑血管病杂志》 2017年第9期805-808,共4页 International Journal of Cerebrovascular Diseases
基金 苏州市科技发展计划课题(SYSD2015046)
关键词 卒中 脑缺血 外周血管疾病 动脉粥样硬化 下肢 超声检查 多普勒 彩色 危险因素 Stroke Brain Ischemia Peripheral Vascuhr Diseases Atherosclerosis Lower Extremity Ultrasonography, Doppler, Color Risk Factors
  • 相关文献

参考文献3

二级参考文献32

  • 1刘鸣,张月辉,吴丽娥.缺血性脑卒中的分型及与预后的关系[J].中国现代神经疾病杂志,2004,4(2):69-71. 被引量:14
  • 2吴丽娥,刘鸣,张月辉,赵晓玲,杨杰,谈颂,张世洪,吴波,谭燕,王清芳,王丽春,李伟.缺血性脑卒中TOAST病因分型和预后[J].中华神经科杂志,2004,37(4):292-295. 被引量:87
  • 3脑血管疾病分类(1995)(中、英文)[J].中华神经科杂志,1996,29(6):376-378. 被引量:430
  • 4各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量:33004
  • 5陈竺.全国第三次死因回顾抽样调查报告[M].北京:中国协和医科大学出版社,2008:11-12.
  • 6Feigha VL, Lawes CM, Bennett DA, et al. Worldwide stroke incidence and early case fatality reported in 56 population-based studies: a systematic review [ J ]. Lancet Neurol, 2009, 8: 355-369.
  • 7Go AS, Mozaffarm D, Roger VL, et al; American I-tmrt Association Statistics Committ and Stroke Statistics Subcommittee. I-Imrt disease and stroke statistics--2014 update: a report from the American Heart Association[J]. Circulation, 2014, 129: e28-e292.
  • 8O'Donnell MJ, Xavier D, Liu L, et al; INTERSTROKE investigators. Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study [ J ]. Lancet, 2010, 376:112-123.
  • 9Sun "H, Chen S, Jiang B, et al. Public knowledge of stroke in Chinese urban residents: a community questionnaire study [ J ]. Neurol Res, 2011, 33: 536-540.
  • 10Meschia JF, Bushnell C, Boden-Albala B, et al; American Heart Association Stroke Council; Council on Cardiovascular and Stroke Nurshag; Council on Clinical Cardiology; Council on Functional Genomics and Translational Biology; Council on Hypertension. Guidelines for the prknary prevention of stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association [ J ]. Stroke, 2014, 45 : 3754-3832.

共引文献118

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部