肥胖型高血压机制及中西医治疗进展

Research Progress of the Mechanism of Obesity Hypertension

肥胖诱发高血压是一个缓慢的进程,其发生机制目前尚未明确,包括肾素-血管紧张素系统、脂联素、胰岛素抵抗、瘦素等诸多影响因素,这些因素可单独或共同作用导致高血压发生。对肥胖型高血压发病机制的研究有助于制订合理的干预措施,降低不良事件的发生率,并对延缓靶器官损害具有重要意义及临床应用价值。另外,对肥胖型高血压治疗采用中医多靶点治疗,既可以减少西药的用量,减少其不良反应,同时服用中药患者的临床症状亦会得到改善,从而提高患者的生存质量。

Obesity-induced hypertension is a slow process ,though its mechanism is not yet clear,it＇s known that multipie factors including renin angiotensin system, adiponectin,insulin resistance, and leptin can act alone or together to lead to high blood pressure. The study of the pathogenesis of obese hypertension can help to develop reasonable intervention measures to reduce the incidence of adverse events, and is of great significance and clinical value to delay the target organ damage. In addition, the use of multiple-target traditional Chinese medicine treatment of obesity-type hypertension treatment, not only can reduce the amount of western medicine, and its adverse reactions, but also improve the clinical symptoms, thereby improve the quality of life of the patients.