不同程度睡眠呼吸暂停综合症患者对精神行为的影响

The Effect of Different Degrees of Sleep Apnea Syndrome on Mental Behavior

目的:探究不同睡眠呼吸暂停低通气指数(AHI)患者各类精神行为的严重程度差异,为睡眠呼吸暂停综合症的诊断与治疗提供理论依据。方法:对2011年11月-2015年11月于我院干预治疗的100例睡眠呼吸暂停综合症患者进行相关精神症状的调查,将睡眠呼吸暂停低通气指数表现为重度的50例患者设为观察组。将呼吸暂停低通气指数表现为轻度以及中度的50例患者设为对照组。比较两组患者记忆力下降、困倦、情绪低落、脾气暴躁的发生率,同时对焦虑(SAS)以及抑郁(SDS)评分进行比较,通过症状自评量表SCL-90评价两组患者自觉精神症状的严重程度进行比较。结果:观察组患者记忆力下降、情绪低落、困倦、脾气暴躁发生率分别为70.00%、68.00%、74.00%、66.00%,对照组分别为34.00%、36.00%、28.00%、38.00%,观察组均显著高于对照组,有统计学意义(χ~2=12.98,10.26,21.17,7.85;P<0.01);观察组患者SAS、SDS评分均显著高于对照组,有统计学意义(t=29.75,7.82;P<0.001);观察组SCL-90中恐怖、偏执、敌意评分与对照组无显著差异,精神病性、抑郁、焦虑、人际关系敏感、强迫症、躯体化、其他评分与对照组差异显著,有统计学意义(t=32.80,12.87,16.19,14.09,14.29,15.52,43.41;P<0.001)。结论:睡眠呼吸暂停综合症患者精神状况较差、焦虑、抑郁症状较为明显,同时睡眠呼吸暂停综合症高的患者各精神行为异常症状较程度低者偏高,因此在睡眠呼吸暂停综合症的日常诊治中应加强对精神行为异常的关注。

Objective：To investigate the differences of severity of various mental behaviorin in patients with differ- ent apnea hypopnea indexes（AHI）,and provide the theoretical basis for the diagnosis and treatment of sleep apnea syndrome.Methods：We investigated related psychiatric symptoms of 100 cases of patients with sleep apnea syndrome in our hospital from November 2011 to November 2015 and grouped 50 cases of patients with severe AHI into the observation group,grouped 50 cases of patients with mild and moderate AHI into the control group.We compared the incidence rate of memory decline, sleepy, depression and irascibility of patients in the two groups, and compared the score of SAS and SDS, the severity of self--conscious mental symptoms of patients in two groups by symptom checklist（SCL--90）.Results：The incidence rate of memory decline, sleepy, depression and i- rascibility of patients in the observation group were 70.00%, 68.00%, 74.00% and 66.000/oo respectively. And they were 34.00 %, 36.00 %, 28.00 %, 38.00 % in the control group. The data in the observation group were significantly larger than those in the control group（X^2 =12.98,10.26,21.17,7.85;P〈O. O1）.The scores of SAS and SDS of pa- tients in the. observation groul~ were significantly larger than those in the control group（t = 29.75,7.82;P〈0.001 ）. There were no significant differences in the scores of terror, stubborn and hostility in SCL--90 of the patients two groups.There were significant differences in psychoticism, depression, anxiety, interpersonal sensitivity, obsession, somatization and other scores between two groups （t = 32.80,12.87,16.19,14.09,14.29,15.52,43.41 ; P〈0.001 ）. Conclusion：Poor mental state,anxiety and depression are obvious in the patients with apnea hypopnea indexes. The abnormal symptoms of patients with severe AHI are more serious than those with mild AHI, thus more attention should be paid in the daily diagnosis and treatment of patients with AHI.