前列腺疾病患者血清前列腺特异性抗原检测分析

Detection and Analysis of Prostate Specific Antigen in Prostate Diseases

目的 了解慢性前列腺炎、急性尿潴留、前列腺癌患者及正常对照组血清总前列腺特异性抗原 (tPSA)水平 ,为临床诊断及治疗前列腺癌提供参考。方法 酶免法检测 35例慢性前列腺炎患者 ,2 4例前列腺增生急性尿潴留患者 ,11例前列腺癌患者及 12 8例健康体检者的血清tPSA水平。结果 正常对照组血清tPSA检测值为 1 15± 0 95ng/ml,急性尿潴留和前列腺癌患者的血清tPSA水平显著高于正常对照组 (P <0 0 1) ,慢性前列腺炎组与正常对照组相比差异也具有显著意义 (P <0 0 1) ,但其值仍在较低水平。

Objective To investigate the serum t PSA levels of chronic prostatitis,acute urinary retention(AUR),and prostatic cancer(Pca),providing reference for the diagnosis and treatment of prostate cancer. Methods The serum t PSA values of 35 cases of chronic prostatitis,24 cases of acute urinary retention(AUR) because of benign prostate hyperplasia(BPH),11 cases of prostate cancer,128 cases of healthy males were detected using EIA. Results There is a significant difference between the t PSA level f AUR group and control group( P <0 01),Also there is a notable difference between the t PSA level of chronic prostatitis group and control group( P <0 01),but they are still in a lower level. Conclusions In order to avoid unnecessary prostate biopsy we should be cautious using t PSA to diagnose Pca.