颈动脉粥样硬化斑块磁共振影像研究的进展

Advances in MRI of carotid atherosclerotic plaque

临床上常以颈动脉狭窄程度作为缺血性脑卒中风险和干预的标准,并已建立了指南。研究发现,有些患者颈动脉粥样硬化的斑块致动脉狭窄并不重,但由于斑块易损不稳定,造成脑梗死的发生率较高,达50%以上,因此易损斑块风险诊断及评估具有重大的临床意义。磁共振检查(MRI)是颈动脉斑块最有效的影像学检查,不同的MRI序列对显示斑块的形态、成分及确定易损程度各有优势。笔者就颈动脉斑块MRI检查推荐的使用序列、易损斑块MRI影像学特点、MRI斑块成像技术的临床应用价值作一综述。

Clinically carotid artery stenosis degree is often used as a standard for ischemic strokerisk and intervention,the guidelines have been established.The study found that the lumen of artery was notseverely stenosis in some patients with carotid atherosclerosis,which is due to the unstable plaque vulnerability.But the incidence of cerebral infarction is more than 50% due to the unstability of plaques.Thus diagnosisand risk assessment of the vulnerable plaque have significantly clinical significance. Magnetic resonanceimaging （MRI） is the most effective imaging examinations of carotid plaques.Different MRI sequences tendedto have different strengths in showing the morphology,composition and fragility of the plaques.The purpose ofthis paper is to make a brief summary of the recommended sequences of MRI plaque imaging,MRI imagingfeatures of vulnerable plaques and the clinical application values of MRI plaque imaging.