有消化道症状儿童幽门螺杆菌感染的血清学调查

Serological investigation of helicobacter pylori infection in children with digestive symptoms

目的:探讨有消化道症状儿童幽门螺杆菌感染的血清学检测结果及影响因素。方法:收治有消化道症状患儿658例,行血清HpIgG抗体检测,分析检测结果。结果:241例血清抗HpIgG抗体阳性,阳性率36.6%;1.5~3岁年龄段阳性率16.7%,显著低于其他两个年龄段(P<0.05);男女占比差异无统计学意义(P>0.05);阳性组单纯父亲或母亲胃病史率56.84%,双亲同时胃病史率22.41%,合计79.25%,与阴性组相比,差异有统计学意义(P<0.05)。结论:有消化道症状儿童幽门螺杆菌感染的发生率较高,因此加强对幽门螺杆菌的预防,最好从婴幼儿开始。

Objective：To explore the serological test results and influencing factors of helicobacter pylori infection in children with digestive symptoms.Methods：658 cases of children with digestive symptoms were selected.They were given serum HpIgG antibody test.We analyzed the test results.Results：The serum anti HpIgG antibody was positive in 241 cases,and the positive rate was 36.6%.The positive rate from 1.5 to 3 years of age was 16.7%,which was significantly lower than the other two age groups（P〉0.05）.There was no statistically significant difference between male and female（P〈0.05）.In the positive group,the rate of stomach trouble in simple fathers or mothers was 56.84%,the rate of stomach trouble in both parents was 22.41%,the total amount was 79.25%;compared with the negative group,the difference was statistically significant（P0.05）.Conclusion：The incidence of helicobacter pylori infection in children with digestive symptoms was higher,therefore,it was best to start to strengthen the prevention of helicobacter pylori from infants and young children.