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低剂量沙利度胺联合化疗治疗多发性骨髓瘤周围神经病变的发生情况 被引量:3

Occurrence of peripheral neuropathy induced by treatment of multiple myeloma with low-dose thalidomide combined chemotherapy
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摘要 多发性骨髓瘤(multiple myeloma,MM)是老年人常见的血液系统恶性肿瘤,至今尚不能完全治愈。沙利度胺通过抑制血管新生、减少IL-6的产生等机制具有抗骨髓瘤作用,近年来广泛应用于MM的治疗。随着临床上的广泛应用,沙利度胺的不良反应越来越受到重视。本研究对61例接受低剂量沙利度胺治疗的MM患者在治疗过程中出现的不良反应进行统计分析,并重点分析其周围神经病变在不同剂量及疗程中的发生率。
出处 《临床血液学杂志》 CAS 2017年第6期870-872,共3页 Journal of Clinical Hematology
基金 上海市嘉定区卫生计生委科研课题(No:2014-KY-11)
关键词 多发性骨髓瘤 沙利度胺 周围神经病变 multiple myeloma thalidomide peripheral neuropathy
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  • 1麦玉洁,李睿,邹德慧,王亚非,赵耀中,杨仁池,王建祥,肖志坚,韩明哲,钱林生,邱录贵.206例多发性骨髓瘤患者不同方案疗效分析[J].中华血液学杂志,2005,26(4):193-196. 被引量:37
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