微创直肠癌全系膜切除术治疗低位直肠癌的临床疗效及对男性盆腔自主神经功能及肿瘤学指标的影响

Clinical Efficacy of Minimally Invasive Total Mesorectal Excision for Low Rectal Cancer and Its Effect on Pelvic Autonomic Nerve Function and Tumor Indicators

目的研究低位直肠癌男性患者应用微创直肠癌全系膜切除手术治疗的临床疗效、盆腔自主神经功能及肿瘤学指标情况。方法对80例低位直肠癌男性患者临床资料加以分析。所有患者均实施直肠癌全系膜切除手术治疗,且按照不同手术方式分成2组。对照组40例患者采取开腹保留患者盆腔自主神经方式,观察组40例患者采取腹腔镜保留患者盆腔自主神经方式。记录且分析2组相关研究结果,包括临床疗效、盆腔自主神经功能及肿瘤学指标。结果观察组术中出血量比对照组少,手术后患者首次排气时间比对照组短,且总并发症率(5.00%)比对照组(25.00%)低,差异均具有可比性(P<0.01);2组在医治后残余尿量、平均尿量与射精功能、勃起功能、排尿功能障碍及肿瘤学指标方面的差异均无统计学意义(P>0.05)。结论临床对低位直肠癌男性患者应用微创直肠癌全系膜切除手术治疗,可优化手术指标,保障术后安全性。

Objective To study the clinical efficacy of minimally invasive total mesorectal excision for low rectal cancer and its effect on pelvic autonomic nerve function and tumor indicators.Methods Selected 80 male patients with low rectal cancer and their clinical data were analyzed.All patients underwent total mesorectal excision for rectal cancer,and were divided into 2 groups,each with 40 cases.The control group received laparotomy pelvic autonomic nerve preservation,the observation group received laparoscopic pelvic autonomic nerve preservation,related study results including efficacy,pelvic autonomic nerve function and tumor indicators of the 2 groups were recorded and analyzed.Results The blood loss in the observation group was less than the control group,the time of first exhaust after the operation in the observation group was shorter than that of the control group,and the total complication rate in the observation group was 5.00%,which was lower than the control group 25.00%,the difference was significant（P 0.01）;Residual urine volume,the average urine volume and ejaculation function,erectile function,urinary dysfunction and tumor markers after treatment of the 2 groups had no significant difference（P 0.05）.Conclusion Minimally invasive total mesorectal excision for low rectal cancer can be optimize the operative index and ensure the postoperative safety.