神经结节病二例

Neurosarcoidosis: two case reports and review of the literature

目的探讨神经结节病的临床特点,提高对神经结节病的诊治水平。方法分析2例神经结节病患者的临床表现、实验室及影像学检查结果、诊治经过和病情转归。结果神经结节病可累及神经系统的不同部位,临床表现多样,如脊髓病变、双侧面神经麻痹和三叉神经痛;脑脊液检查无特异性改变,影像学检查往往可以发现神经系统、肺部和淋巴结病变。结论当临床出现原因不明的脊髓病变或多发脑神经损害,应考虑神经结节病的可能。

Objective To study the clinical characteristics, diagnosis and treatment of neurosarcoidosis （ NS ）. Method We retrospectively analyzed the clinical features, laboratory and imaging results, treatment, and outcome of two patients with NS. Results NS involved in many parts of the nervous system, resulting in diverse manifestations, such as myelopathy, bilateral facial nerve palsy and trigeminal neuralgia. No specific change was found in cerebrospinal fluid. Imaging studies could often detect the lesions in the nervous system, lungs and lymph nodes. Conclusion NS should be considered when myelopathy or multiple cranial neuropathies without known causes occur.