PET-CT诊断巨细胞动脉炎4例并文献复习

PET/CT for diagnosing 4 cases of giant cell arteritis and literature review

目的探讨PET-CT在诊断巨细胞动脉炎(GCA)中的临床意义。方法回顾性分析该院收治的4例GCA患者的临床表现、实验室器械检查及PET-CT结果,并予相关文献进行复习。结果该院4例及文献中29例患者年龄都大于50岁;临床上主要表现为发热、体质量下降、肌痛等非特异性症状;实验室检查主要表现为ESR、CRP升高;PET-CT提示主动脉及其一级分支管壁连续性弥漫性代谢升高;该院4例患者最大摄取标准值(SUVmax)2.5~9.6。结论 PET-CT对诊断GCA尤其是早期或临床表现不典型者有一定临床价值,对病变范围的确定和疗效判断有一定的意义。

Objective To investigate the clinical significance of PET/CT in the diagnosis of giant cell arteritis.Methods The clinical manifestations,laboratory detection and PET/CT results in 4 patients with giant cell arteritis treated in this hospital were retrospectively analyzed.And the relevant literatures were reviewed.Results The age of 4 cases in this hospital and 29 cases in literatures all were over 50 years old;clinical manifestations were mainly the non-specific symptoms such as fever,weight loss and myalgia;the laboratory detection results mainly manifested by the increase of ESR and CRP;PET-CT indicated that the continuous diffuse metabolism of the wall in aorta and its primary branching was elevated;the maximal standardized uptake value（SUVmax）of 4 cases in this hospital was 2.5-9.6.Conclusion PET/CT has a certain value for diagnosing giant cell arteritis,especially the patients with early stage or atypical clinical manifestations.PET/CT has certain significance for determining the lesion range and judging the curative effect.