PET/CT与增强CT对肺癌淋巴结诊断及分期的比较分析

Comparison of PET/CT and enhanced CT in diagnosis and staging of lymph node metastasis in lung cancer

目的:比较正电子发射型计算机断层显像(PET)/电子计算机断层扫描(CT)与增强CT对肺癌淋巴结及其分期的诊断价值。方法:选取80例(560枚病灶)肺癌患者,均行PET/CT和CT增强扫描检查,以病理检查结果作为金标准,比较PET/CT与增强CT的阳性预测值、阴性预测值、特异度、灵敏度及分期诊断准确率。结果:PET/CT的阳性预测值、阴性预测值、特异度及灵敏度均明显高于增强CT,差异有统计学意义(P<0.05);PET/CT与增强CT对N0期淋巴结的诊断准确率比较差异无统计学意义(P>0.05),PET/CT对N1和N2期淋巴结的诊断准确率明显高于增强CT,差异有统计学意义(P>0.05)。结论:与增强CT扫描比较,PET/CT检查技术在诊断肺癌及淋巴结分期方面效果更好,可作为临床诊断的重要依据。

Objective： To compare diagnostic values of positron emission computed tomography（ PET）/computed technology（ CT） and enhanced CT in diagnosis and staging of lung cancer lymph node metastasis. Methods： Selection of 80 patients with lung cancer（ 560 lesions） were retrospectively analyzed. All patients underwent PET/CT and CT enhanced scan,and the pathological results were taken as the gold standard. The positive predictive values,negative predictive values,specificities,sensitivities and staging diagnosis rates of PET/CT and enhanced CT were compared. Results： The positive predictive value,negative predictive value,specificity and sensitivity of PET/CT were significantly higher than those of enhanced CT,and the differences were statistically significant（ P〈0.05）. Further,the difference of the diagnostic accuracy of PET/CT and enhanced CT in the diagnosis of N0 lymph node was not statistically significant（ P 〉0. 05）; however,that of the diagnosis rate of N1 and N3 lymph nodes was statistically significant（ P〉 0.05）. Conclusions： Compared with enhanced CT scan,PET/CT examination in the diagnosis of lung cancer and lymph node staging is more effective and can be used as an important evidence for clinical diagnosis.