胆宁片对36例2型糖尿病患者胆囊结石及便秘的治疗效果

Efficacy of Danning tablets in treatment of type 2 diabetes mellitus with gallstone and constipation

目的:观察胆宁片治疗2型糖尿病合并胆囊结石及便秘患者的临床疗效和不良反应。方法:选择2型糖尿病合并胆囊结石及便秘患者36例,服用胆宁片每次5片,每日3次,疗程6个月。治疗前后观察胆囊结石、便秘变化情况及糖化血红蛋白水平,同时观察患者治疗期间的不良反应。结果:胆囊结石治疗总有效率为77.8%;便秘治疗总有效率为83.3%;治疗前后对比糖化血红蛋白水平明显下降(P<0.05)。治疗期间均未出现明显不良反应。结论:结论胆宁片在治疗2型糖尿病合并胆囊结石及便秘方面有较好的治疗效果,不良反应少。

Objective： To observeclinical efficacy and adverse reactions of Danning tablets in treatment of type 2 diabetes mellitus with gallstone and constipation. Methods： A total of 36 patients with type 2 diabetes mellitus with gallstone and constipation were involved in this study and received the therapy of Danning tablets（ 5 tablets/time,3 times/day） for 6 months. The changes of gallstone and constipation and the glycosylated hemoglobin levels before and after the treatment and the adverse reactions during the treatment were observed. Results： The total efficiencies of gallstone and constipation were 77. 8% and 83. 3%,respectively. A significant improvement in HBA1 cwas achieved 6 months after the treatment compared with baseline values（ P 〈0. 05）. No adverse reactions occurred during the treatment. Conclusions： Danning tablets in the treatment of type 2 diabetes mellitus with gallstone and constipation is effective with less adverse reactions.