火针在女性黄褐斑(气滞血瘀证)治疗中的应用价值

Application Value of Fire-needling in the Treatment of Female Chloasma of Qi Stagnation and Blood Stasis Pattern

目的:探讨火针治疗女性黄褐斑(气滞血瘀证)的临床疗效。方法:将90例女性黄褐斑患者按照随机数字表法分为两组,每组45例。对照组给予还原型谷胱甘肽片、复方维生素C钠咀嚼片和维生素E胶囊口服,火针组在对照组治疗基础上给予火针治疗。比较两组皮损积分、血清超氧化物歧化酶(SOD)和丙二醛(MDA)水平,并比较两组生活质量评分和治疗总有效率。结果:治疗4周后,火针组皮损面积积分、皮损颜色积分、血清MDA水平、生活质量评分(心理状态、生理状态、日常活动、社交娱乐)均低于对照组(P<0.01),血清SOD水平高于对照组(P<0.01),治疗总有效率高于对照组(P<0.05),差异均有统计学意义。结论:火针疗法可有效改善皮损评分,提高患者生活质量,治疗女性黄褐斑(气滞血瘀证)疗效确切。

Objective: To investigate the clinical curative effect of fire-needling for female chloasma of qi stagnation and blood stasis pattern. Methods: 90 patients were randomly divided into the fire-needling group( n =45) and the control group( n = 45). Reduced glutathione tablet,compound vitamin C sodium tablet,and vitamin E capsule were given to the patients in the control group; on which basis,the patients in the fire-needling group were also treated with fire-needling. Skin lesion integral,serum levels of superoxide dismutase( SOD)and malondialdehyde( MDA),scores of life quality( mental and physical state,daily activities,and social entertainment),and total effective rate were compared between the two groups. Results: Integrals of lesion area and skin color,serum levels of MDA,and scores of life quality in the fire-needling group were all significantly lower than those in the control group after four-week treatment( P < 0. 01); SOD level of the fire-needling group was obviously higher than that of the control group( P < 0. 01); the total effective rate was higher than that of the control group( P < 0. 05). Conclusion: The therapy of fire-needling has positive curative effect on female chloasma of qi stagnation and blood stasis pattern,with its action of reducing the skin lesion and improving life quality.