火龙灸对急性腰扭伤患者细胞免疫功能的影响

Impacts of Dragon Moxibustion on Cellular Immune Function in the Treatment of Acute Lumbar Sprain

目的:探讨火龙灸对急性腰扭伤患者细胞免疫功能的影响。方法:采用随机单盲对照研究,2012年9月到2017年1月选择在我院诊治的急性腰扭伤患者132例作为研究对象,根据随机信封抽签原则分为观察组与对照组各66例,对照组给予中药穴位注射治疗,观察组给予火龙灸治疗,两组都治疗观察1个月,记录两组预后与细胞免疫功能变化情况。结果:所有患者都完成治疗,治疗过程中无严重不良反应发生。经过治疗,在总有效率方面,观察组达到97.0%,对照组达到86.4%,观察组比对照组高(P<0.05)。治疗后观察组与对照组的疼痛评分别为(1.22±0.42)分和(2.45±0.89)分,都明显低于治疗前的(4.59±0.81)分和(4.61±0.81)分(P<0.05),治疗后观察组的疼痛评分也低于对照组(P<0.05)。治疗后观察组的CD3^+值显著升高,CD4^+值显著降低,与治疗前比较存在明显差异(P<0.05);而对照组的CD3^+值和CD4^+值治疗前后没有明显差异(P>0.05)。结论:采用火龙灸对急性腰扭伤患者进行治疗,能够有效提升治疗效果与有效缓解疼痛,且不会增加不良反应的发生,其作用机制可能与促进机体免疫功能恢复有关。

Objective: To explore the effects of dragon moxibustion on cellular immune function in the treatment of acute lumbar sprain. Methods: 132 patients with acute lumbar sprain were randomly divided into the observation group( n = 66) and the control group( n = 66). The control group was given acupoint injection,and the observation group was treated with dragon moxibustion. The prognosis and cellular immune function were observed in the two groups after one-month treatment. Results: All patients completed the treatment and there were no serious adverse reactions occurred during the treatment. After the treatment,the total effective rate of the observation group and the control group were 97. 0% and 86. 4% respectively,and it was significantly higher in the observation group than that in the control group( P < 0. 05). Pain scores of the observation group and the control group were 1. 22 ± 0. 42 and 2. 45 ± 0. 89 respectively after the treatment,which were both significantly lower than 4. 59 ± 0. 81 and 4. 61 ± 0. 81 correspondingly before the treatment( P < 0. 05); of which the observation group was superior to the control group( P < 0. 05). CD3^+ level was increased,and CD4^+ level was decreased significantly in the observation group after the treatment,compared to those before the treatment( P <0. 05); however,there were no significant changes in terms of the values of CD3^+ and CD4^+ in the control group( P > 0. 05). Conclusion: The therapy of dragon moxibustion for acute lumbar sprain can effectively improve the therapeutic effect and relieve pain without increasing the incidence of adverse reactions. Its mechanism may be related to promoting the recovery of immune function.