三九胃泰颗粒联合雷贝拉唑钠肠溶胶囊治疗慢性浅表性胃炎的效果及安全性分析

Analysis of the efficacy and safety of Sanjiu Weitai granules combined with rabeprazole sodium enteric-coated capsules in the treatment of chronic superficial gastritis

目的分析三九胃泰颗粒联合雷贝拉唑钠肠溶胶囊治疗慢性浅表性胃炎的效果及安全性。方法采用随机平行对照法将2015年2月至2016年3月103例慢性浅表性胃炎患者依据治疗方法不同分为对照组51例及观察组52例。对照组患者给予雷贝拉唑钠肠溶胶囊,观察组患者给予三九胃泰颗粒联合雷贝拉唑钠肠溶胶囊治疗。观察两组患者治疗后的临床疗效及安全性。结果观察组总有效率(98.08%)高于对照组(88.24%,P<0.05);观察组治疗期间不良反应发生率(7.69%)低于对照组(7.84%),但差异未见统计学意义(P>0.05)。结论三九胃泰颗粒联合雷贝拉唑钠肠溶胶囊,治疗慢性浅表性胃炎效果确切,安全性高,临床可广泛应用。

Objective To analyze the effect and safety of Sanjiu Weitai granules combined with rabeprazole sodium enteric-coated capsules in the treatment of chronic superficial gastritis. Methods One hundred and three patients with chronic superficial gastritis from February 2015 to March 2016 were divided into control group（ 51 cases） and observation group（ 52 cases） according to the different treatment methods. The control group was treated with rabeprazole sodium enteric-coated capsules,the observation group was treated with Sanjiu Weitai granules combined with rabeprazole sodium enteric-coated capsules. The clinical efficacy and safety of the two groups after treatment were observed. Results The total effective rate of the observation group（ 98. 08%） was higher than that of the control group（ 88. 24%,P〈0. 05）; the incidence of adverse reactions in the observation group（ 7. 69%） was lower than that in the control group（ 7. 84%）,but the difference was not significant（ P〉0. 05）. Conclusions Sanjiu Weitai granules combined with rabeprazole sodium enteric-coated capsules is effective on chronic superficial gastritis,has high safety,and can be widely applied in clinic.