前庭阵发症的临床研究进展

Progress in clinical research of vestibular paroxysmia

前庭阵发症是外周性眩晕的一种,主要表现为是短暂、频繁的发作性眩晕,持续数秒到几分钟,伴或不伴耳部症状。诊断主要依赖特征性的临床表现,MRI可以发现第Ⅷ颅神经根血管压迫表现,发病机制类似于三叉神经痛、半面痉挛,其治疗主要依靠卡马西类药物进行控制,无法耐受药物治疗的患者需要进行手术治疗。

Vestibular paroxysmia（ VP） is one of the peripheral vestibular disorders. The main clinical symptom of VP is brief attacks of rotatory or postural vertigo lasting seconds to a few minutes,with or without ear symptoms. In most patients,a high-resolution MRI showed neurovascular compression（ NVCC） in the terminal area of the vestibulocochlear nerve. Analogously with trigeminal neuralgia,hemifacial spasm,the NVCC of the eighth cranial nerve is the cause of these symptoms in VP and medical treatment with carbamazepine is effective,patients who are unable to tolerate the drug need surgery.