血清C-反应蛋白检测对小儿支原体肺炎感染的诊断价值

Clinical value of serum C-reactive protein detection in diagnosis of pediatric mycoplasma pneumonia infection

目的分析血清C-反应蛋白(CRP)检测对小儿支原体肺炎感染的诊断价值。方法选取支原体肺炎、细菌性肺炎患儿及进行健康体检的儿童各60例,分别检测治疗前和治疗1周后三组儿童血清CRP水平,比较其血清CRP阳性率。结果治疗前,支原体肺炎组血清CRP水平和血清CRP阳性率明显高于健康对照组,细菌性肺炎组明显高于健康对照组和支原体肺炎组;治疗后1周,细菌性肺炎组和支原体肺炎组患儿血清CRP水平和血清CRP阳性率均较治疗前明显下降,且细菌性肺炎组下降幅度更大(P<0.05)。结论小儿细菌性肺炎血清CRP阳性率高于支原体肺炎,血清CRP检测可作为鉴别细菌性肺炎和支原体肺炎的有效方法之一。

Objective To evaluate the clinical valua of C-reactive protein（ CRP） for the diagnosis of children with mycoplasma pneumonia infection. Methods Sixty children diagnosed with mycoplasma pneumonia,60 children dsagnosed with bacteria pneumonia and 60 children receiving the medical examination were involved in this research. The CRP levels of the three groups before treatment and after one week of the treatment were detected. The psitive rates of serum CRP were compared. Results Before treatment,the CRP level and the positive rate of serum CRP of the mycoplasma pneumonia group were significant higher than those of the control group,the CRP level and the positive rate of serum CRP of the bacteria pneumonia group were significant higher than those of the mycoplasma pneumonia group and the control group. After one week of the treatment,the CRP levels and the positive rates of serum CRP of the two pneumonia groups significantly decreased comparing with those before treatment,the decrease of the CRP level and the positive rate of serum CRP of the bacteria pneumonia group were still significantly higher than those of the mycoplasma pneumonia group and the control group（ P〈0. 05）. Conclusions The positive rate of serum CRP in children with bacterial pneumonia is higher than that of mycoplasma pneumonia. The detection of CRP can be used as an effective way to identify the bacteria pneumonia and the mycoplasma pneumonia.