痰热清注射液联合还原型谷胱甘肽钠治疗劳力型热射病患者的效果观察

Efficacy of Tanreqing injection combined with reduced glutathione sodium on patients with exertional heatstroke

目的 观察痰热清注射液联合还原型谷胱甘肽钠治疗劳力型热射病患者的临床效果。方法 将符合研究条件的62例劳力型热射病患者随机分为对照组（30例）和治疗组（32例）。对照组给予物理降温、抗凝、抗感染、脑细胞保护剂、营养、床旁血滤、输注血小板、维持水电解质平衡等综合治疗；治疗组在对照组基础上给予痰热清注射液及还原型谷胱甘肽钠。比较两组患者的临床治疗效果。结果 治疗组患者体温恢复正常时间及入住重症监护室时间均明显少于对照组（P〈0.05）；治疗组患者分别从治疗后第3天和第5天开始，感染学指标、生化指标及凝血指标均优于对照组，差异有统计学意义（P〈0.05）。结论 痰热清注射液联合还原型谷胱甘肽钠治疗劳力型热射病，可提高降温效果，有利于患者病情的恢复。

Objective To observe the clinical efficacy of Tanreqing injection combined with reduced glutathione sodium on patients with exertional heatstroke.Methods A total of 62 patients with exertional heatstroke were randomly divided into the control group （30 cases） and the treatment group （32 cases）. The patients of control group were given physical hypothermia, anticoagulation, anti infection, brain cell protection, nutrition, bedside blood filtration, transfusion of platelets, maintenance of water, electrolyte balance, and so on. The patients of treatment group were given Tanreqing injection and reduced glutathione sodium chloride on the basis of the control group. The clinical effects of the two groups were compared.Results The normal temperature recovery time and ICU time in the treatment group were significantly shorter than those in the control group （P〈0.05）; the infection index, biochemical indicators and coagulation indexes in the treatment group from third days and fifth days after treatment were better than those in the control group, the differences were significant （P〈0.05）.Conclusions Tanreqing injection combined with reduced glutathione sodium in the treatment of exertional heartstroke can improve the cooling effect, and it is conducive to the recovery of the patient＇s condition.