摘要
马钱子碱对癌症细胞的主要抑制机制包括诱导癌细胞凋亡、抑制癌细胞增殖、阻止癌细胞黏附转移等.文章通过对近年来马钱子碱及其制剂抗肿瘤作用的研究,提出马钱子碱相关制剂尚需与现有药物进行疗效和不良反应比较,以评价马钱子碱抑制肿瘤的效果,并对其抑瘤机制进行进一步探索,为患者提供安全、高效的治疗药物.
The inhibiting mechanisms of brucine to cancer cells included inducing the apoptosis of cancer cells, inhibiting the proliferation of cancer cells, preventing cell adhesion and transfer. This paper reviews the function of brucine and its anti-tumor preparations, and compares the efficacy and adverse reactions between brucine related preparations and traditional drugs to evaluate its anti-tumor effects. Furthermore, more exploration on the inhibiting mechanisms is necessary for the patients to obtain safe and effective drugs.
出处
《肿瘤研究与临床》
CAS
2017年第11期784-788,共5页
Cancer Research and Clinic
关键词
抗肿瘤药
植物
马钱子碱
制剂
药物疗法
Anti-neoplastic angets,phytogenic
Brucine
Preparations
Drug therapy
