儿童活体肝移植供体术后生活质量评估

Quality of life of donors after pediatric living donor liver transplantation

目的调查儿童活体肝移植(Living donor liver transplantation,LDLT)供体供肝捐献术后生活质量情况。方法回顾性分析2014年9月至2016年11月复旦大学附属华山医院18例儿童活体肝移植手术供者临床资料。采用供体特异性量表(Donor-specific survey,DSS)评估18位供体术后生活质量情况。结果 18组手术顺利完成。经过中位时间为14.5月随访后,所有供受体均健康存活。16(88.9%)位供者认为捐献前后健康状况无变化,14(77.8%)位供者术后出现可耐受临床不适症状。17(94.4%)位供者认为自尊心与术前一样或比术前好,无供者出现抑郁症状。13(72.2%)名供者已恢复工作,剩余5(27.8%)名也认为待业状态与捐献无关。所有供者对捐献经历较为满意并愿意再次捐献。结论儿童活体肝移植供体术后躯体健康、心理状态及社会功能评估均较为满意,生活质量较高。

Objective To evaluate the postoperative quality of life of donors in pediatric living donor liver transplantation（ LDLT）. Methods The clinical data of 18 pediatric LDLT donors who were underwent the liver donation surgery in Huashan Hospital Affiliated to Fudan University from September 2014 to November 2016 were analyzed retrospectively. The Donor-specific survey（ DSS）was adopted to evaluate the quality of life after the donation. Results 18 LDLT were performed successfully. All the donors and recipients survived healthily with a median time of 14. 5 months of follow-up. 16（ 88. 9%） donors reported the same state of health after the surgery,while 14（ 77. 8%） donors experienced uncomfortable symptoms which were tolerable. 17 donors reported that their self-esteems were same as or better than before donation and no depression occurred. 13（ 72. 2%） donors has returned to their work and the remaining 5（ 27. 8%） believed that there was no direct relationship between the unemployment and donation. All the donors were satisfied with the donation and would like to donate again. Conclusion The outcome of physical health,psychological states and social function is favorable in donors after the pediatric LDLT. The donors can lead a life with a satisfying quality of life.