CT灌注成像在急性胰腺炎疗效观察中的价值研究

The value of CT perfusion imaging in observing acute pancreatitis' curative effect

目的:分析CT灌注成像在急性胰腺炎(AP)疗效观察中的应用价值。方法:选择中、重度胰腺炎(MSAP、SAP)患者25例,采用东芝AQUILION ONE 320排CT进行扫描灌注成像,于入院48~72h行第1次CT灌注扫描,1周左右重复做灌注扫描,其中14例于治疗2周左右再次重复灌注扫描,肉眼观察灌注伪彩图的变化。利用最大斜率法进行灌注分析,测量胰腺灌注的时间-密度曲线(TDC)以及灌注参数动脉灌注量(AF),分析急性胰腺炎治疗前后AF值的变化。结果:中重度急性胰腺炎TDC呈缓升平坦型,峰值低;治疗前后灌注伪彩图显示灌注逐渐升高,统计学分析显示治疗前后AF值之间比较差异有统计学意义(P<0.05)。结论:CT灌注成像对急性胰腺炎疗效观察具有重要的临床意义。

Objective:To analyze the value of CT perfusion imaging in the observation of acute pancreatitis' curative effect.Methods:Twenty-five patients with moderately severe acute pancreatitis(MSAP)or severe acute pancreatitis(SAP)underwent pancreas perfusion by Toshiba 320 row CT.All underwent the first CT perfusion imaging within 48~72 hours after hospitalization,and then were examined repeatedly within a week or so,among which 14 cases were examined again after two weeks' treatment.The changes of perfusion pseudo-color map were observed by the naked eye.Data was analyzed with the maximum slope method by the perfusion software.These parameters of time density curve(TDC)and artery blood flow(AF)were measured respectively,and the changes of artery blood flow(AF)before and after treatment of acute pancreatitis were analyzed.Conclusion:CT perfusion imaging has an important clinical significance in observing acute pancreatitis' curative effect.