肠内营养液间歇泵入对颅脑创伤患者胃肠功能及喂养耐受性的影响

Effect of intermittent infusion of enteral nutrition solution on gastrointestinal function and feeding tolerance in craniocerebral trauma patients

目的:探讨肠内营养液间歇泵入对颅脑创伤患者胃肠功能及喂养耐受性的影响。方法:2016年1~12月选取本院神经外科收治的120例颅脑创伤患者,随机将患者等分为观察组和对照组,两组患者均行整蛋白型肠内营养制剂,对照组采用持续泵入输注,观察组采用间歇泵入输注,即输注90 min暂停150 min,每天4次,比较两组胃肠功能及喂养耐受性情况。结果:观察组胃肠功能评分均低于对照组(P<0.05),且患者胃液残留量少于对照组(P<0.05),而胃液p H值低于对照组(P<0.05)。观察组喂养耐受、7 d营养达标高于对照组(P<0.05),而胃肠应激性溃疡、消化道出血低于对照组(P<0.05)。结论:肠内营养液间歇泵入能有效提高重症颅脑损伤患者肠内营养耐受性,改善患者营养状况及胃肠功能,促进患者预后。

Objective： To explore the effect of intermittent infusion of enteral nutrition solution on gastrointestinal function and feeding tolerance in craniocerebral trauma patients. Methods： A total of 120 craniocerebral trauma patients admitted to the department of neurosurgery in our hospital from January to December 2016 were selected,and randomly and equally divided into observation group and control group. Patients in the two groups received whole protein enteral nutrition preparation. The control group was treated with continuous pump infusion,and the observation group was treated with intermittent pump infusion,namely,an infusion for 90 minutes with pause for 150 minutes and 4 times per day. The gastrointestinal function and feeding tolerance were compared between the two groups. Results： The gastrointestinal function score in the observation group was lower than that in the control group（ P〈0. 05）,and the gastric juice residue of the patients was less than that in the control group（ P〈0. 05）,while the p H value of gastric juice was lower than that in the control group（ P〈0. 05）. The feeding tolerance and the 7 d nutritional level in the observation group were higher than those in the control group（ P〈0. 05）,while the gastrointestinal stress ulcer and gastrointestinal bleeding were lower than those in the control group（ P〈0. 05）. Conclusion： Intermittent infusion of enteral nutrition solution can effectively improve the enteral nutrition tolerance in patients with severe craniocerebral injury,the nutritional status and gastrointestinal function of patients,and promote the prognosis of patients.