三氯吡氧乙酸衍生物的合成与生物活性研究

Synthesis and Biological Activity of Triclopyr Derivatives

三氯吡氧乙酸分别与3-苯氧-1-丙醇和3-苯氧-1-丙胺反应合成了2个三氯吡氧乙酸衍生物,其化学结构经~1H NMR和高分辨质谱确证。初步除草活性测试结果表明,在150 g/hm^2有效成分用量下,2个新化合物对双子叶杂草具有较好的抑制活性,其中化合物4a对苘麻的抑制率达100%。

Two triclopyr derivatives were synthesized by reaction of triclopyr with 3-phenoxy-1-propanol or 3-phenoxy-1-propylamine. Their structures were confirmed by ^1H NMR and HR-MS. The preliminary bioassay results showed that the title compounds had some herbicidal activities at the dosage of 150 g/hm^2. The compound 4a exhibited 100% inhibition to Abutilon theophrasti Medicus.