关注眼病人群流行病学研究模式的转变

Focusing on the methodology shift in epidemiological study of eye diseases

随着慢性病逐渐成为我国人群健康的首要威胁以及大众对眼健康质量要求的迅速提升，眼病人群的流行病学研究模式必须尽快转变，即应开展大规模、多中心和前瞻性的人群队列研究，在具有不同性别、年龄、民族和生活习惯等的人群中广为验证；构建类似广义线性、非线性混合效应等新型分析模型，更好地分析环境外因和个体内因的交互作用；开展系统流行病学和空间流行病学研究，去解构眼病病因的多元化，更准确地推导病因，最终为特定患者的个性化精准预测、诊断和治疗提供循证医学的最佳证据。

As chronic diseases gradually become the primary threat to the health of Chinese population and the rapid increase in the need of high eye health quality,the population-based epidemiological study of eye disease in China should be conducted in the following mode：large-scale, muhicenter, and prospective cohort studies in different gender,age, ethnicity and living habits population, with new analytical models similar to generalized linear and nonlinear mixed effects to better analyze the interaction between environmental causes and individual internal factors. The systematic epidemiology and spatial epidemiology concepts are suggested to be included in eye research,in order to deconstruct the cause of eye disease diversification. All these facilitate precision prediction,diagnosis and treatment of individual patient.