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肝素诱导的血小板减少症临床诊疗的循证进展 被引量:6

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摘要 肝素诱导的血小板减少症(heparin induced thrombocytopenia,HIT)是肝素类药物(包括普通肝素和低分子肝素)治疗过程中由抗体介导产生的副作用,主要表现为血小板数量显著降低,严重者可导致静、动脉血栓形成。HIT发病率较低,但临床后果严重。在住院患者中,各种原因所致的血小板减少症和肝素暴露普遍存在,使疑似HIT患者显著多于确诊患者,因此如何准确识别HIT、及时有效治疗以及避免过度治疗已成为临床医师面临的重要挑战”。
出处 《中华医学杂志》 CAS CSCD 北大核心 2017年第46期3667-3670,共4页 National Medical Journal of China
基金 国家重点研发计划精准医学研究专项(2016YFC0905600,2016YFC0905601)
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