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充分水化对对比剂肾病的预防作用——倾向评分配比分析 被引量:4

The effects of adequate hydration on prevention of contrast-induced nephropathy:a propensity score-matched analysis
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摘要 目的用倾向评分配比分析探讨充分水化对冠状动脉造影术(CA)或经皮冠状动脉介入治疗术(PCI)所致对比剂肾病(CIN)的预防作用。方法以2010年首都医科大学附属北京安贞医院3993例行CA或PCI的患者为研究对象,并以是否按照2006年"国际对比剂肾病专家共识"建议的方案进行了水化处理将上述患者分为充分水化(48例)和未行水化(共3945例)两类,而后应用倾向评分匹配法从未行水化患者中筛选出与充分水化患者匹配的等数量(48例)患者,构成了本研究的充分水化组及未水化组(各48例)。观察并比较了这两组患者的术后CIN发生率、院内不良事件发生率及全因死亡率。结果未水化组的CIN发病率为16.7%(8/48例),充分水化组为0,两组比较差异具有统计学意义(P=0.006);未水化组的院内不良事件发生率为2.1%,充分水化组为0,但两组间差异尚无统计学意义(P=1.000);两组均无死亡病例。结论充分水化处理可有效预防CIN发生。 Objective To investigate the effects of adequate hydration on prevention of contrast-induced nephropathy (CIN), through propensity score matching analysis, in the hospitalized patients undergoing coronary angiography (CA) or percutaneous coronary intervention (PCI). Methods A total of 3993 patients hospitalized in Beijing Anzhen Hospital in 2010 were collected. Among them, 48 patients accepted adequate hydration and 3945 patients did not accept hydration. Using propensity score matching method 48 patients without hydration, who matched with the adequately hydrated patients, were screened out. In this way, the adequate hydration group and the non-hydration group (48 patients in each group) in this study were formed. 2-he incidence of CIN, the adverse events and mortality during hospitalization were observed and compared between these two groups. Results The incidence of CIN was 16.7% in the non-hydration group and 0 in the adequate hydration group (P=0.006). The incidence of in-hospital adverse events was 2.1% in the non-hydration group and 0 in the adequate hydration group (P=1.000). No patients died in both groups. Conclusion Adequate hydration can effectively prevent CIN.
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2017年第12期1086-1089,共4页 Chinese Journal of Practical Internal Medicine
基金 首都卫生发展科研专项(首发2011-2006-07)
关键词 水化处理 对比剂肾病 冠状动脉造影术 经皮冠状动脉介入治疗术 hydration treatment contrast-induced nephropathy coronary angiography percutaneous coronary intervention
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  • 1Austin PC. A critical appraisal of propensity score matching in the medical literature between 1996 and 2003. Star Med, 2008,27(12):2037-2049.
  • 2Rubin DB, Thomas N. Matching using estimated propensity scores: relating theory to practice, Biometrics, 1996, 52: 249-264.
  • 3Rosenbaum PR, Rubin DB. The central role of file propensity score in observational studies for causal effects. Biometrika, 1983, 70:41-55.
  • 4Rosenbaum PR, Rubin DB. Constructing a control group using multivariate matched sampling methods that incorporate the propensity score. Am Stat, 1985, 39:33-38.
  • 5Rubin DB. Bias reduction using Mahalanobis metric matching. Biometrics, 1980, 36:293-298.
  • 6Baser O. Too much ado about propensity score models? Comparing methods of propensity score matching. Value Health, 2006, 9(6): 377-385.
  • 7D' Agostino RB. Propensity score methods for bias reduction in the comparison of a treatment to a nortrandomized control group. Stat Med, 1998,17 (19) : 2265-2281.
  • 8Jones AS. Maternal alcohol abuse/dependence, children's behavior problems, and home environment: estimates from the National Longitudinal StLrvey of Youth using propensity score matching. J Stud Alcohol Drugs, 2007, 68(2) : 266-275.
  • 9Trujillo A J, Portillo JE, Vernon JA. The impact of subsidized health insurance for the poor: evaluating the Colombian experience using propensity score matching. Int J Health Care Finance Econ, 2005, 5(3) :211-239.
  • 10Do MP, Kincaid DL. Impact of an entertainment-education television drama on health knowledge and behavior in Bangladesh: an application of propensity score matching. J Health Commun, 2006, 11 (3) : 301-325.

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