如何更好地识别多系统萎缩

How to better identify multiple system atrophy

多系统萎缩很容易误诊为帕金森病或其他不典型帕金森病，由于他们不但具有相同的病理改变，临床表现亦有许多相似之处，所以早期诊断比较困难。如何更好地识别多系统萎缩，对其未来治疗具有决定性作用，应该引起广大临床医师的关注。本综述旨在研究多系统萎缩的自主神经功能障碍和早期临床表现，检测方法及影像学改变特点，以便为早期多系统萎缩的诊断提供有利的依据和帮助。

Multiple system atrophy（MSA） can be easily misdiagnosed as Parkinson＇s disease （PD） or other forms of atypical Parkinsonism, because they not only share similar pathological changes but also present many common clinical manifestations, which make early diagnosis difficult. How to better identify MSA plays a decisive role in subsequent treatment and should concern physicians. The aim of this review is to examine the autonomic nervous dysfunction and its early clinical manifestations,detection methods, and imaging characteristics of MSA, and thus to provide helpful guidelines for the early diagnosis of MSA.