二甲双胍联合沙格列汀治疗2型糖尿病的临床效果分析

Clinical Effect of Metformin Combined With Saxagliptin in the Treatment of Type 2 Diabetes Mellitus

目的探讨二甲双胍联合沙格列汀治疗2型糖尿病的临床效果。方法选取我院收治的82例2型糖尿病患者为研究对象,将其分为对照组(41例)与观察组(41例)。对照组给予二甲双胍口服治疗,观察组在此基础上,联合沙格列汀治疗,观察两组效果。结果观察组血糖指标的控制情况优于对照组,差异有统计学意义(P<0.05);两组不良反应发生率对比,差异无统计学意义(P>0.05)。结论二甲双胍联合沙格列汀治疗2型糖尿病效果显著,可有效控制患者血糖指标。

Objective To explore the clinical effect of metformin combined withsaxagliptin in the treatment of type 2 diabetes mellitus. Methods 82 casesof patients with type 2 diabetes mellitus in our hospital were selected as the research objects, and they were divided into control group（41 cases） and observation group（41 cases）. The control group was treated with metformin orally, the observation group, on this basis of the treatment methods of control group, combined with saxagliptin treatment, to observe the effect of the two groups. Results The control of blood glucose in the observation group was significantly better than that in the control group, the difference was statistically significant（P 〈 0.05）; The incidence of adverse reactions in the two groups had no significant difference（P 〉 0.05）. Conclusion Metformin combined with saxagliptin in the treatment of type 2 diabetes has significant effect, which can effectively control blood glucose indicators.