血液透析联合血液灌流治疗尿毒症顽固性高血压的临床效果

Clinical effect of hemodialysis combined with hemoperfusion in uremic patients with refractory hypertension

目的探讨血液透析联合血液灌流对尿毒症顽固性高血压的治疗效果。方法选取我院2015年4月至2017年4月收治的86例尿毒症顽固性高血压患者,将之随机分为对照组与观察组,各43例。对照组给予血液透析治疗,观察组给予血液透析联合血液灌流治疗。比较两组患者的治疗效果。结果观察组患者的治疗总有效率显著高于对照组(P<0.05);治疗前,两组患者收缩压、舒张压水平及应用降压药物的种类比较,差异不显著(P>0.05);治疗后,两组患者的收缩压、舒张压水平下降,应用降压药物的种类减少,且观察组均优于对照组(P<0.05)。结论血液透析联合血液灌流治疗尿毒症顽固性高血压效果显著,具有临床推广价值。

Objective To investigate the effect of hemodialysis combined with hemoperfusion on uremic and refractory hypertension. Methods A total of 86 uremic patients with refractory hypertension in our hospital from April 2015 to April2017 were selected and randomly divided into control group and observation group, with 43 cases in each group. The control group was given hemodialysis treatment, and the observation group was given hemodialysis combined with hemoperfusion treatment. The treatment effects were compared between the two groups. Results The total effective rate of the observation group was higher than that of the control group（P〈0.05）. Before treatment, the differences in the levels of systolic blood pressure, diastolic blood pressure and the types of antihypertensive drugs between the two groups were not significant（P〉0.05）; after treatment, the levels of systolic blood pressure, diastolic blood pressure and the types of antihypertensive drugs decreased in both groups, and those in the observation group were lower than the control group（P〈0.05）. Conclusion Hemodialysis combined with hemoperfusion in uremic patients with obstinate hypertension has significant effect, which has value of clinical promotion.