标准四联疗法及序贯疗法治疗Hp阳性消化性溃疡的临床效果

Clinical effect of standard quadruple therapy and sequential therapy in the treatment of Hp positive peptic ulcer

目的探讨标准四联疗法及序贯疗法治疗Hp阳性消化性溃疡的临床效果。方法将我院2014年1月至2016年10月收治的Hp阳性消化性溃疡患者86例作为研究对象,随机分为研究组和对照组,各43例。研究组患者采用序贯疗法进行治疗,对照组患者采用标准四联疗法进行治疗。比较两组患者的临床疗效。结果治疗后,研究组Hp根除率为95.35%,明显高于对照组的83.72%(P<0.05);研究组患者的溃疡治疗总有效率为97.67%,明显高于对照组的83.72%,差异具有统计学意义(P<0.05)。结论使用序贯疗法治疗Hp阳性消化性溃疡临床效果显著,Hp根除率高,值得临床推广使用。

Objective To investigate the clinical effect of standard quadruple therapy and sequential therapy in the treatment of Hp positive peptic ulcer. Methods A total of 86 cases of Hp positive peptic ulcer patients admitted in our hospital from January 2014 to October 2016 were selected as the study objects, all the patients were randomly divided into study group and control group, with 43 cases in each group. The study group was treated with sequential therapy, the control group was given standard quadruple therapy. The clinical effects of the two groups were compared. Results The Hp eradication rate of the study group was 95.35%, which was higher than 83.72% of the control group（P〈0.05）. The total effective rate of ulcer treatment in the study group was 97.67%, which was higher than 83.72% in the control group（P〈0.05）. Conclusion Sequential therapy has significant clinical effect in the treatment of Hp positive peptic ulcer, with high Hp eradication rate, which can be popularized in clinical practice.