糖尿病合并尿路感染的病原菌分布及耐药性分析

Analysis of distribution and drug resistance of pathogens in patients with diabetes mellitus combined with urinary tract infection

目的探究糖尿病合并尿路感染的病原菌分布情况及耐药性。方法将我院2014年12月至2016年12月收治的257例糖尿病合并尿路感染患者作为研究对象,采集患者的尿液标本,对其实施细菌培养并进行药敏试验。研究糖尿病患者合并尿路感染的病原菌分布情况及耐药性。结果 257例患者中,共收集220株(85.60%)病原菌,其中革兰阴性杆菌的比例(70.91%)显著高于革兰阳性球菌(25.45%)及真菌(3.64%)(P<0.05);不同病原菌对抗菌药物的耐药性有所差别。结论糖尿病合并尿路感染的病原菌以革兰阴性杆菌为主,不同病原菌的耐药性有差异,临床医师应结合患者的药敏试验结果为其合理选择抗菌药物。

Objective To investigate the distribution and drug resistance of pathogens in diabetes mellitus patients combined with urinary tract infection. Methods A total of 257 diabetes mellitus patients with urinary tract infection admitted in our hospital from December 2014 to December 2016 were selected as the study subjects. The urine samples of the patients were collected and subjected to bacterial cultivation and drug sensitivity test. The distribution and drug resistance of pathogens in diabetes mellitus combined with urinary tract infection were studied. Results Among the 257 patients, 220（85.60%） pathogens were collected, the proportion of Gram-negative bacilli（70.91%） was significantly higher than that of Gram-positive cocci（25.45%） and fungi（3.64%）, the differents were statistically significant（P〈0.05）. The resistance of different pathogens to antimicrobial drugs was different. Conclusion The pathogens of diabetes mellitus patients complicated with urinary tract infection are mainly Gram-negative bacilli, and the resistance of different pathogens to antimicrobial drugs will be different. The clinicians should refer to the patient＇s drug sensitivity test results to reasonably select antibiotics for patients.