腭咽成型术后患者采用右美托咪啶与咪达唑仑镇静的临床效果分析

Clinical effect analysis of dexmedetomidine and midazolam in patients undergoing uvulopalatopharyngoplasty

目的分析腭咽成型术后患者采用右美托咪啶与咪达唑仑镇静的临床效果。方法选取我院收治的腭咽成型术后患者80例,根据用药不同分为观察组和对照组,各40例。观察组患者采用右美托咪啶治疗,对照组患者采用咪达唑仑治疗。比较两组患者术后麻醉苏醒1~2 h的镇静躁动程度评分、心率、平均动脉压及血氧饱和度。结果观察组患者术后麻醉苏醒1~2 h的镇静躁动程度评分明显低于对照组,差异具有统计学意义(P<0.05)。手术后,观察组患者的心率及平均动脉压水平明显低于对照组,差异具有统计学意义(P<0.05);两组患者的血氧饱和度水平比较,差异无统计学意义(P>0.05)。结论腭咽成型术后患者应用右美托咪啶,可以有效降低患者的躁动,值得临床推广应用。

Objective To analyze the clinical effect of dexmedetomidine and midazolam in patients undergoing uvulopalatopharyngoplasty. Methods Eighty cases of patients undergoing uvulopalatopharyngoplasty in our hospital were selected and divided into observation group and control group according to different medication, with 40 cases in each group.The observation group received dexmedetomidine, and the control group accepted midazolam. The scores of sedation and agitation, heart rate, mean arterial pressure and blood oxygen saturation after 1-2 h of anesthesia were compared between the two groups. Results The score of sedation and agitation after 1-2 h of anesthesia in the observation group was lower than that in the control group, the difference was statistically significant（P〈0.05）. After operation, the heart rate and mean arterial pressure levels in the observation group were lower than those in the control group, the difference was statistically significant（P〈0.05）; but there was no significant difference in the blood oxygen saturation level between the two groups（P〉0.05）. Conclusion Using dexmedetomidine in patients undergoing uvulopalatopharyngoplasty can effectively reduce the restlessness, which is worthy of clinical application and promotion.