经尿道膀胱肿瘤电切术与1.9μm激光治疗膀胱癌的临床效果比较

Clinical effects comparison of transurethral resection of bladder tumor and 1.9 μm continuous-wave laser resection in the treatment of bladder cancer

目的比较经尿道膀胱肿瘤电切术与1.9μm激光膀胱肿瘤切除术治疗膀胱癌的临床疗效。方法按照随机数字表法将我院收治的42例膀胱癌患者分为观察组和对照组,各21例。观察组患者采用1.9μm激光膀胱肿瘤切除术,对照组患者应用经尿道膀胱肿瘤电切术。比较两组患者治疗前、后的炎症因子水平、手术情况及术后并发症发生情况。结果治疗后,两组患者的白介素-6、白介素-10及肿瘤坏死因子-α水平均明显高于治疗前,且观察组明显优于对照组(P<0.05)。观察组患者术后肉眼血尿和膀胱冲洗时间均明显短于对照组(P<0.05);观察组患者并发症总发生率为9.52%,明显低于对照组的42.86%(P<0.05)。结论采用1.9μm激光膀胱肿瘤切除术治疗膀胱癌,安全性高,并发症少,切除肿瘤彻底,值得临床推广应用。

Objective To compare the clinical efficacy of transurethral resection of bladder tumor and 1.9 μm continuous-wave laser resection in the treatment of bladder cancer. Methods A total of 42 patients with bladder cancer who admitted in our hospital were randomly divided into observation group and control group, with 21 cases in each group. The observation group received 1.9 μm continuous-wave laser resection, and the control group accepted transurethral resection of bladder tumor. The levels of inflammatory factors, operation situation and postoperative complications were compared between the two groups. Results After treatment, the levels of IL-6, IL-10 and TNF-α in the two groups were higher than those before treatment, and those in the observation group were better than the control group（P〈0.05）. The gross hematuria and bladder washout time of observation group were shorter than those of the control group（P〈0.05）. The incidence of postoperative complications was 9.52% of the observation group, which was lower than 42.86% of the control group（P〈0.05）.Conclusion The 1.9 μm continuous-wave laser resection in the treatment of bladder cancer has high safety, less complications and radical resection of tumor, which is worthy of application and popularization in clinic.