补肾壮骨法治疗血透患者皮肤瘙痒38例疗效观察

Clinical Observation of 38 Hemodialysis Patients with Itchy Skin by Kidney-reinforcing and Bone-strengthening Method

目的观察补肾壮骨法治疗血透患者皮肤瘙痒的临床疗效。方法将76例合并皮肤瘙痒的血透患者随机分为治疗组38例和对照组38例。2组患者均维持原有稳定饮食习惯和原血液透析治疗方案、治疗基础疾病及伴发症状,治疗组同时加用补肾壮骨汤治疗。2组均治疗6个月,观察治疗前及治疗后的皮肤瘙痒积分、血清全段甲状旁腺激素(i PTH)、血钙及血磷变化,治疗后评价临床疗效。结果治疗组临床疗效总有效率为84.21%,对照组为57.89%,治疗组患者的临床疗效较对照组患者佳(P<0.05)。2组治疗后皮肤瘙痒积分均较治疗前有明显下降(P<0.05),且治疗组皮肤瘙痒积分下降明显优于对照组(P<0.05);2组治疗后血钙、血磷、i PTH均明显改善(P<0.05),且治疗组血钙、血磷、i PTH水平明显好于对照组(P<0.05)。结论补肾壮骨法可以明显缓解血透患者的皮肤瘙痒症状。

Objective: To observe the clinical effect of Kidney-reinforcing and Bone-strengthening Method on the treatment of hemodialysis patients with itchy skin. Methods: 76 patients were randomly divided into a treatment group and a control group,38 cases per group. The patients of the two groups were maintained their original stable diet and original hemodialysis treatment program and the treatment of underlying diseases and associated symptoms,but the treatment group was added with Kidney-reinforcing and Bone-strengthening Method. The two groups were treated for6 months. The changes of pruritus scores,i PTH,serum calcium and serum phosphorus were observed before and after treatment and the clinical effects were evaluated after treatment. Results: The total effective rate was 84. 21% in the treatment group and 57. 89% in the control group. The clinical effect of the treatment group was better than that of the control group( P < 0. 05). The pruritus scores of both groups after the treatment were significantly lower than those before the treatment( P < 0. 05),and the pruritus scores in the treatment group were significantly lower than those in the control group( P < 0. 05). The levels of serum calcium,serum phosphorus and i PTH of the two groups significantly improved( P < 0. 05),and the levels of serum calcium,phosphorus and i PTH in the treatment group were significantly better than those in the control group( P < 0. 05). Conclusion: Kidney-reinforcing and Bone-strengthening Method can relieve itchy skin in hemodialysis patients.