摘要
Three new o-hydroxy Schiff bases, L1, L2 and L3, were derived from the 1：1 M condensation of substituted salicylaldehyde with tris base and were characterized by FT-IR, ^1H NMR and ^13C NMR spectroscopies. The crystal structure of L1 was also determined by single-crystal X-ray analysis, and it exists as a zwitterionic form in the solid state, with the H atom of the phenol group being transferred to the imine N atom. It adopts an E-configuration about the central C=N double bond. In addition, the biological activity assay was carried out and the results show that the Schiff-base compounds have a diverse range of biological activities against the fungi tested, which suggests great potential applications in antifungal fields in the future.
Three new o-hydroxy Schiff bases, L1, L2 and L3, were derived from the 1：1 M condensation of substituted salicylaldehyde with tris base and were characterized by FT-IR, ^1H NMR and ^13C NMR spectroscopies. The crystal structure of L1 was also determined by single-crystal X-ray analysis, and it exists as a zwitterionic form in the solid state, with the H atom of the phenol group being transferred to the imine N atom. It adopts an E-configuration about the central C=N double bond. In addition, the biological activity assay was carried out and the results show that the Schiff-base compounds have a diverse range of biological activities against the fungi tested, which suggests great potential applications in antifungal fields in the future.
基金
financially supported by the Natural Science Foundation of Hunan Province(2017JJ3093)
the Scientific Research Fund of Hunan Provincial Education Department(No.16B104)
