乳腺增生动物模型制备规范(草案)

Specifications for Preparation of Mammary Gland Hyperplasia Models(Draft)

乳腺增生是一种与内分泌功能紊乱密切相关的既非炎症又非肿瘤的乳腺增生性病变,是以乳腺腺泡、导管的上皮细胞及结缔组织增生为基本病理变化的一类疾病的总称。现乳腺增生模型有根据内分泌激素失调引起的病因性动物模型,也有针对症状设计的动物模型。基于对中西医临床病症特点分析及大量动物实验研究基础上,形成了乳腺增生动物模型制备规范(草案),为相关的实验研究提供参考。

Mammary gland hyperplasia is a class of diseases in general closely related to endocrine dysfunction,which is neither inflammation nor tumor of the breast hyperplasia lesions,and its basic pathological changes is the hyperplasia of breast acinar, duct epithelial cells and connective tissue. The mammary gland hyperplasia model is based on endocrine hormone disorders caused by the cause of animal models,but also for the design of animal models with symptoms. Based on the analysis of characteristics of clinical symptoms of Chinese and western medicine,and a large number of animal experiments,preparation specifications（ draft） of mammary gland hyperplasia animal model are formed.