临床中药合理用药的安全性及应对策略分析

Safety and Strategy Analysis of Rational Use of Traditional Chinese Medicine

目的观察分析临床中药合理用药的安全性,并制定相应的应对策略。方法选择2015年2月—2016年2月实施临床中药合理用药应对策略前处方作为对照组,选择2016年3月—2017年3月实施应对策略后处方为观察组,每组各124张处方。比较两组不合理用药发生率及应对策略。结果观察组不合理用药发生率为5.65%,低于对照组的33.06%,差异具有统计学意义(P<0.05)。结论影响临床中药合理用药安全性的因素较多,应严格控制用量及用法、注意中西联合药物的合理性、正确炮制、坚持辨证论治原则等,提高中药临床用药的安全性,减少药物不良反应。

Objective To observe and analyze the safety of clinical rational use of Chinese medicine, and to formulate appropriate coping strategies. Methods From February 2015 to February 2016, the prescriptions which were before the implementation of clinical rational use of traditional Chinese medicine strategies were selected as the control group, from March 2016 to March 2017, the prescriptions which were after the implementation of strategies were selected as the observation group, 124 prescriptions in each group, the incidence of irrational use of drug and the coping strategies were compared between the two groups. Results The incidence of irrational use of drug in the observation group was 5.65%, which was significantly lower than 33.06% in the control group, and the difference was statistically significant （P〈0.05）. Conclusion There are many factors influencing thesafety of TCM clinical rational drug use, we should strictly control the dosage and usage, pay attention to reasonable combination of traditional Chinese and Western medicine and correct processing, adhere to the dialectical theory, improve the safety of clinical medication of traditional Chinese medicine, reduce adverse drug reactions.