中药保留灌肠预防及治疗放射性直肠炎的进展

Research Progress of TCM Enema in Prevention and Treatment of Radiation Enteritis

放射性肠炎是接受放射治疗的常见并发症,目前尚无药物预防及治疗的标准策略。中药保留灌肠作为主要治疗方法之一,有疗效确切、操作简单、副作用少等诸多优点,临床上被广泛应用。单纯采用中药灌肠剂,或者中药灌肠剂与其他疗法联合治疗放射性肠炎均能改善临床症状,提高患者生存质量。可见,中药灌肠剂在放射性肠炎的治疗中具有不可取代的优势地位,其中西医结合治疗形式多样,疗效显著,安全性好。但目前缺乏多中心、大样本的临床研究,且中药的作用机制研究很少。

Radiation enteritis is a common complication of radiotherapy. There is no standard strategy for drug prevention and treatment. The retention of traditional Chinese medicine enema is one of the main treatment methods, it has many advantages, such as exact curative effect, simple operation and fewer side effects, and which is widely used in clinic. TCM enema alone, or combination treatment with other treatment methods can both improve clinical symptoms, and the quality of living. The traditional Chinese medicine enema has an unreplaceable advantage in the treatment of radiation enteritis, in which the combination of traditional Chinese medicine and western medicine has a variety of forms, the efficacy is significant and the safety is good. However, there are few clinical studies on multi-center and large samples, and few studies have been done on the mechanism of TCM.